N,N'-Bis(2-Hydroxyethyl)Ethylenediamine
CAS4439-20-7
N,N'-Bis(2-hydroxyethyl)ethylenediamine (CAS 4439-20-7) is a symmetrical amino alcohol carrying two secondary amines and two primary hydroxyl groups on an ethylenediamine backbone. The four donor and reactive sites make it a versatile building block for chelating ligands, heterocycles and functional amines. KingPharm supplies research and production quantities with a batch-specific certificate of analysis.
- CAS No.
- 4439-20-7
- Formula
- C6H16N2O2
- Mol. weight
- 148.20 g/mol
- Appearance
- Yellow to Light yellow Crystalline Powder
Product Description
N,N'-Bis(2-hydroxyethyl)ethylenediamine (C6H16N2O2, MW 148.20) is an ethylenediamine in which each nitrogen bears one 2-hydroxyethyl group. It is a white to pale yellow solid that is soluble in water, with a literature melting point of 98–100 °C.
The two secondary amine nitrogens and the two hydroxyl oxygens can act as an N2O2 donor set toward metal ions, or as nucleophilic handles for alkylation, acylation and ring-forming reactions. Because both ends of the molecule are identical, it allows symmetrical bis-functionalization in a single step.
Compared with unsubstituted ethylenediamine, the hydroxyethyl arms add extra coordination sites and hydrophilicity while leaving one N–H on each nitrogen available for further derivatization. Unlike the unsymmetrical isomer N,N-bis(2-hydroxyethyl)ethylenediamine, the N,N'-substitution pattern gives a symmetrical product, which simplifies downstream purification and characterization.
For purchasing, confirm the isomer by CAS number (4439-20-7, not the N,N-isomer), and check assay, appearance and water content on the COA. The material is hygroscopic as an amino alcohol; keep containers tightly closed and protected from light.
Chemical Specifications
Identifiers
| CAS number | 4439-20-7 |
|---|---|
| Product name | N,N'-Bis(2-Hydroxyethyl)Ethylenediamine |
| Chinese name | N,N'-双（2-羟乙基）乙二胺 |
| IUPAC name | 2-[2-(2-hydroxyethylamino)ethylamino]ethanol |
| Synonyms | 2,2’-(1,2-ethanediyldiimino)bis-ethano |
| Chinese synonyms | 固化剂2号; N,N-Bis(2-羟乙基)乙二胺; 2,2-(羟乙基)乙二胺; N,N-双(2-羟乙基)乙二胺 |
| Molecular formula | C6H16N2O2 |
| Molecular weight | 148.20 g/mol |
| EC number | 224-656-4 |
| MDL number | MFCD00002842 |
| PubChem CID | 78179 |
| InChIKey | GFIWSSUBVYLTRF-UHFFFAOYSA-N |
| SMILES | C(CNCCO)NCCO |
Physical and chemical properties
| Appearance | Yellow to Light yellow Crystalline Powder |
|---|---|
| Melting Point | 92.0-99.0 ( ℃ ) |
| Boiling Point | 146.245 ( ℃ ) |
Applications
N,N'-Bis(2-hydroxyethyl)ethylenediamine is mainly used as a bifunctional building block in the following areas.
Chelating ligand synthesis
Serves as an N2O2 donor ligand or ligand precursor for transition-metal coordination complexes.
Pharmaceutical intermediate
Used as a symmetrical diamine building block in the synthesis of drug candidates and related intermediates.
Heterocycle and functional amine chemistry
Provides amine and hydroxyl handles for ring-forming reactions and further N- or O-derivatization.
Curing agent and polymer additive
Used in industrial formulations as a curing agent where both amine and hydroxyl reactivity are useful.
Quality Documentation
The following documents can be provided for N,N'-Bis(2-Hydroxyethyl)Ethylenediamine to support technical evaluation and purchasing. Documents are issued for the specific grade and batch supplied.
-
Certificate of Analysis (COA) Batch-specific test results against the specification.
-
Product specification The release specification with test items, limits and methods.
Packaging, Storage & Transport
| Storage Temp | 室温, 干燥通风，密闭容器<br>Room Temp., Dry, Tighten Container ( ℃ ) |
|---|---|
| Available pack sizes | 25 kg, 10 kg, 1 kg, 500 g, 100 g, 25 g |
Read the current safety data sheet before handling. Packaging can be adapted to the order quantity and destination.
Frequently Asked Questions
How does it differ from N,N-bis(2-hydroxyethyl)ethylenediamine?
In CAS 4439-20-7 the two hydroxyethyl groups sit on different nitrogens (N,N'), giving a symmetrical molecule with two secondary amines. The N,N-isomer carries both groups on one nitrogen and has a free primary amine, so the two are not interchangeable; order by CAS number.
Why use it instead of ethylenediamine?
The hydroxyethyl arms add two extra donor and reactive sites and increase water compatibility, while each nitrogen keeps one N–H for further substitution. This is useful when a symmetrical, more hydrophilic diamine scaffold is required.
How should it be stored?
Keep the container tightly closed in a cool, dry place, protected from light and moisture. Supplier data list refrigerated storage (2–8 °C); follow the conditions on the label and COA.
What is the CAS number of N,N'-Bis(2-Hydroxyethyl)Ethylenediamine?
The CAS Registry Number of N,N'-Bis(2-Hydroxyethyl)Ethylenediamine is 4439-20-7. N,N'-Bis(2-Hydroxyethyl)Ethylenediamine is also known as 2,2’-(1,2-ethanediyldiimino)bis-ethano.
What is the molecular formula and molecular weight of N,N'-Bis(2-Hydroxyethyl)Ethylenediamine?
The molecular formula of N,N'-Bis(2-Hydroxyethyl)Ethylenediamine is C6H16N2O2, and its molecular weight is 148.20 g/mol.
What is N,N'-Bis(2-Hydroxyethyl)Ethylenediamine used for?
N,N'-Bis(2-hydroxyethyl)ethylenediamine is mainly used as a bifunctional building block in the following areas.
Which quality documents are available for N,N'-Bis(2-Hydroxyethyl)Ethylenediamine?
The following documents are available for N,N'-Bis(2-Hydroxyethyl)Ethylenediamine: Certificate of Analysis (COA); Product specification. Contact KingPharm to request the documents for a specific batch.
How can I request a quotation for N,N'-Bis(2-Hydroxyethyl)Ethylenediamine?
Send an inquiry for N,N'-Bis(2-Hydroxyethyl)Ethylenediamine (CAS 4439-20-7) with the required quantity, target specification, destination country and any documentation requirements. KingPharm will confirm availability, packaging, lead time and price.
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